Quality You Can Trust

Our products are manufactured under contract by Adaptogen Pharmaceutical, Inc.

Safety & Security

Our products are manufactured in a state-of-the-art facility that has acquired many certifications set at the international level.

Safety & Security

Clinical Trials

Extensive clinical trials have been conducted to obtain more advanced evidence on the safety and functionality of our ingredients.

Clinical trials of Bijun hyaluronic acid supplement tablets

*Clinical trials of ECM-E have been conducted by Adaptogen Pharmaceutical, Inc. Although there is no guarantee of efficacy, the safety of ECM-E has been confirmed.

Clinical Research Results by Adaptogen Pharmaceutical (Japanese)
https://ecme.adaptgen.co.jp/clinical.html

List of Publications on ECM-E (Japanese)
https://ecme.adaptgen.co.jp/thesis.html

11 International Patents Obtained in 9 Countries

ECM-E, a highly absorbable hyaluronic acid produced by our original manufacturing method, has been granted 11 international patents. Its quality has been recognized worldwide.

Patent No. 3596777 Japan
US 6403560 United States of America
Patent No. 0395298 Republic of Korea
Patent No. 0443653 Republic of Korea
Patent No. 0447327 Republic of Korea
EP 1174142 Federal Republic of Germany
EP 1174142 United Kingdom of Great Britain and Northern Ireland
EP 1174142 Republic of France
EP 1174142 Swiss Confederation
EP 1174142 Principality of Liechtenstein
Patent No. I262081 Taiwan