Quality You Can Trust
Our products are manufactured under contract by Adaptogen Pharmaceutical, Inc.
Safety & Security
Our products are manufactured in a state-of-the-art facility that has acquired many certifications set at the international level.
Clinical Trials
Extensive clinical trials have been conducted to obtain more advanced evidence on the safety and functionality of our ingredients.
*Clinical trials of ECM-E have been conducted by Adaptogen Pharmaceutical, Inc. Although there is no guarantee of efficacy, the safety of ECM-E has been confirmed.
Clinical Research Results by Adaptogen Pharmaceutical (Japanese)
https://ecme.adaptgen.co.jp/clinical.html
List of Publications on ECM-E (Japanese)
https://ecme.adaptgen.co.jp/thesis.html
11 International Patents Obtained in 9 Countries
ECM-E, a highly absorbable hyaluronic acid produced by our original manufacturing method, has been granted 11 international patents. Its quality has been recognized worldwide.
| Patent No. 3596777 | Japan |
| US 6403560 | United States of America |
| Patent No. 0395298 | Republic of Korea |
| Patent No. 0443653 | Republic of Korea |
| Patent No. 0447327 | Republic of Korea |
| EP 1174142 | Federal Republic of Germany |
| EP 1174142 | United Kingdom of Great Britain and Northern Ireland |
| EP 1174142 | Republic of France |
| EP 1174142 | Swiss Confederation |
| EP 1174142 | Principality of Liechtenstein |
| Patent No. I262081 | Taiwan |